List of Home Depot Locations in South Carolina, United States

Last Updated: Dec 28, 2025

How many Home Depots are there in South Carolina, United States?

There are 26 Home Depots in South Carolina, United States, spread over 24 cities. The city with the highest number of Home Depots in this region is Spartanburg with 2 stores.

Top 10 Cities with most Home Depots Stores in South Carolina, United States

City	Home Depots Count
Spartanburg	2
Columbia	2
Bluffton	1
Charleston	1
Dentsville	1
Easley	1
Florence	1
Gantt	1
Garden City	1
Greenville	1

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Table of Home Depots Locations in South Carolina, United States

Showing 1 - 26 of 26 Locations

Store ID	Store Name	Country	City	Region	ZIP Code	Address	Coordinates	Phone Number	Pro Desk Phone	Store Page URL	Opening Hours
1103	Charleston	United States	North Charleston	South Carolina	29406	7554 Northwood Blvd	[32.93898,-80.04494]	(843)569-3773	(843)820-1400	https://www.homedepot.com/l/Charleston/SC/Charleston/29406/1103	Monday - 6:00 AM to 9:00 PM Tuesday - 6:00 AM to 9:00 PM Wednesday - 6:00 AM to 6:00 PM Thursday - 9:00 AM to 8:00 PM Friday - 6:00 AM to 9:00 PM Saturday - 6:00 AM to 9:00 PM Sunday - 8:00 AM to 8:00 PM
1104	North Greenville	United States	Sans Souci	South Carolina	29609	2490 N Pleasantburg Dr	[34.89138,-82.38195]	(864)232-0510	(864)242-2700	https://www.homedepot.com/l/North-Greenville/SC/Greenville/29609/1104	Monday - 6:00 AM to 9:00 PM Tuesday - 6:00 AM to 9:00 PM Wednesday - 6:00 AM to 6:00 PM Thursday - 9:00 AM to 8:00 PM Friday - 6:00 AM to 9:00 PM Saturday - 6:00 AM to 9:00 PM Sunday - 8:00 AM to 8:00 PM
1105	Anderson	United States	Anderson	South Carolina	29621	3427 Clemson Blvd	[34.54605,-82.67585]	(864)964-0820	(864)964-8400	https://www.homedepot.com/l/Anderson/SC/Anderson/29621/1105	Monday - 6:00 AM to 9:00 PM Tuesday - 6:00 AM to 9:00 PM Wednesday - 6:00 AM to 6:00 PM Thursday - 9:00 AM to 8:00 PM Friday - 6:00 AM to 9:00 PM Saturday - 6:00 AM to 9:00 PM Sunday - 8:00 AM to 8:00 PM
1106	Lexington	United States	Lexington	South Carolina	29072	5600 Sunset Blvd	[33.99619,-81.22750]	(803)359-1194	(803)358-2168	https://www.homedepot.com/l/Lexington/SC/Lexington/29072/1106	Monday - 6:00 AM to 9:00 PM Tuesday - 6:00 AM to 9:00 PM Wednesday - 6:00 AM to 6:00 PM Thursday - 9:00 AM to 8:00 PM Friday - 6:00 AM to 9:00 PM Saturday - 6:00 AM to 9:00 PM Sunday - 8:00 AM to 8:00 PM
1108	East Spartanburg	United States	Spartanburg	South Carolina	29307	2300 E Main Street	[34.97998,-81.87512]	(864)579-0382	(864)237-6702	https://www.homedepot.com/l/East-Spartanburg/SC/Spartanburg/29307/1108	Monday - 6:00 AM to 9:00 PM Tuesday - 6:00 AM to 9:00 PM Wednesday - 6:00 AM to 6:00 PM Thursday - 9:00 AM to 8:00 PM Friday - 6:00 AM to 9:00 PM Saturday - 6:00 AM to 9:00 PM Sunday - 8:00 AM to 8:00 PM
1109	Sandhills	United States	Columbia	South Carolina	29229	285 Forum Drive	[34.12657,-80.87254]	(803)419-9336	(803)419-6102	https://www.homedepot.com/l/Sandhills/SC/Columbia/29229/1109	Monday - 6:00 AM to 9:00 PM Tuesday - 6:00 AM to 9:00 PM Wednesday - 6:00 AM to 6:00 PM Thursday - 9:00 AM to 8:00 PM Friday - 6:00 AM to 9:00 PM Saturday - 6:00 AM to 9:00 PM Sunday - 8:00 AM to 8:00 PM
1110	East Columbia	United States	Dentsville	South Carolina	29206	7701 Two Notch Rd	[34.07904,-80.94528]	(803)736-1666	(803)865-2425	https://www.homedepot.com/l/East-Columbia/SC/Columbia/29223/1110	Monday - 6:00 AM to 9:00 PM Tuesday - 6:00 AM to 9:00 PM Wednesday - 6:00 AM to 6:00 PM Thursday - 9:00 AM to 8:00 PM Friday - 6:00 AM to 9:00 PM Saturday - 6:00 AM to 9:00 PM Sunday - 8:00 AM to 8:00 PM
1112	West Columbia	United States	Columbia	South Carolina	29212	5200 Fernandina Rd	[34.07669,-81.15081]	(803)781-0877	(803)749-4404	https://www.homedepot.com/l/West-Columbia/SC/Columbia/29212/1112	Monday - 6:00 AM to 9:00 PM Tuesday - 6:00 AM to 9:00 PM Wednesday - 6:00 AM to 6:00 PM Thursday - 9:00 AM to 8:00 PM Friday - 6:00 AM to 9:00 PM Saturday - 6:00 AM to 9:00 PM Sunday - 8:00 AM to 8:00 PM
1114	Rock Hill	United States	Rock Hill	South Carolina	29732	2815 Home Depot Blvd	[34.97864,-80.98486]	(803)909-2420	(803)909-2402	https://www.homedepot.com/l/Rock-Hill/SC/Rock-Hill/29730/1114	Monday - 6:00 AM to 9:00 PM Tuesday - 6:00 AM to 9:00 PM Wednesday - 6:00 AM to 6:00 PM Thursday - 9:00 AM to 8:00 PM Friday - 6:00 AM to 9:00 PM Saturday - 6:00 AM to 9:00 PM Sunday - 8:00 AM to 8:00 PM
1115	Hilton Head	United States	Bluffton	South Carolina	29910	20 Gateway Village Road	[32.25511,-80.84531]	(843)815-7000	(843)815-1406	https://www.homedepot.com/l/Hilton-Head/SC/Bluffton/29910/1115	Monday - 6:00 AM to 9:00 PM Tuesday - 6:00 AM to 9:00 PM Wednesday - 6:00 AM to 6:00 PM Thursday - 9:00 AM to 8:00 PM Friday - 6:00 AM to 9:00 PM Saturday - 6:00 AM to 9:00 PM Sunday - 8:00 AM to 8:00 PM
1116	Myrtle Beach	United States	Myrtle Beach	South Carolina	29577	951 Oak Forest Ln	[33.70485,-78.91409]	(843)916-2229	(843)445-8402	https://www.homedepot.com/l/Myrtle-Beach/SC/Myrtle-Beach/29577/1116	Monday - 6:00 AM to 9:00 PM Tuesday - 6:00 AM to 9:00 PM Wednesday - 6:00 AM to 6:00 PM Thursday - 9:00 AM to 8:00 PM Friday - 6:00 AM to 9:00 PM Saturday - 6:00 AM to 9:00 PM Sunday - 8:00 AM to 8:00 PM
1117	Aiken	United States	Aiken	South Carolina	29803	1785 Whiskey Rd	[33.52449,-81.72195]	(803)648-6291	(803)643-2984	https://www.homedepot.com/l/Aiken/SC/Aiken/29803/1117	Monday - 6:00 AM to 9:00 PM Tuesday - 6:00 AM to 9:00 PM Wednesday - 6:00 AM to 6:00 PM Thursday - 9:00 AM to 8:00 PM Friday - 6:00 AM to 9:00 PM Saturday - 6:00 AM to 9:00 PM Sunday - 8:00 AM to 8:00 PM
1118	East Charleston	United States	Charleston	South Carolina	29414	2008 Magwood Dr	[32.81337,-80.04535]	(843)556-2447	(843)852-5220	https://www.homedepot.com/l/East-Charleston/SC/Charleston/29414/1118	Monday - 6:00 AM to 9:00 PM Tuesday - 6:00 AM to 9:00 PM Wednesday - 6:00 AM to 6:00 PM Thursday - 9:00 AM to 8:00 PM Friday - 6:00 AM to 9:00 PM Saturday - 6:00 AM to 9:00 PM Sunday - 8:00 AM to 8:00 PM
1119	Greenville	United States	Greenville	South Carolina	29615	79 Woodruff Industrial Ln	[34.82780,-82.30771]	(864)284-0991	(864)284-2084	https://www.homedepot.com/l/Greenville/SC/Greenville/29607/1119	Monday - 6:00 AM to 9:00 PM Tuesday - 6:00 AM to 9:00 PM Wednesday - 6:00 AM to 6:00 PM Thursday - 9:00 AM to 8:00 PM Friday - 6:00 AM to 9:00 PM Saturday - 6:00 AM to 9:00 PM Sunday - 8:00 AM to 8:00 PM
1120	Summerville	United States	Summerville	South Carolina	29483	190 Marymeade Dr	[33.03072,-80.16143]	(843)851-0468	(843)851-4014	https://www.homedepot.com/l/Summerville/SC/Summerville/29483/1120	Monday - 6:00 AM to 9:00 PM Tuesday - 6:00 AM to 9:00 PM Wednesday - 6:00 AM to 6:00 PM Thursday - 9:00 AM to 8:00 PM Friday - 6:00 AM to 9:00 PM Saturday - 6:00 AM to 9:00 PM Sunday - 8:00 AM to 8:00 PM
1121	North Myrtle Beach	United States	North Myrtle Beach	South Carolina	29582	620 Hwy 17 N	[33.83281,-78.67054]	(843)280-9908	(843)281-3204	https://www.homedepot.com/l/North-Myrtle-Beach/SC/North-Myrtle-Beach/29582/1121	Monday - 6:00 AM to 9:00 PM Tuesday - 6:00 AM to 9:00 PM Wednesday - 6:00 AM to 6:00 PM Thursday - 9:00 AM to 8:00 PM Friday - 6:00 AM to 9:00 PM Saturday - 6:00 AM to 9:00 PM Sunday - 8:00 AM to 8:00 PM
1122	Murrells Inlet	United States	Garden City	South Carolina	29576	12262 Hwy 17 Bypass	[33.57688,-79.03119]	(843)357-3777	(843)357-7534	https://www.homedepot.com/l/Murrells-Inlet/SC/Murrells-Inlet/29576/1122	Monday - 6:00 AM to 9:00 PM Tuesday - 6:00 AM to 9:00 PM Wednesday - 6:00 AM to 6:00 PM Thursday - 9:00 AM to 8:00 PM Friday - 6:00 AM to 9:00 PM Saturday - 6:00 AM to 9:00 PM Sunday - 8:00 AM to 8:00 PM
1124	Simpsonville	United States	Simpsonville	South Carolina	29680	669 Fairview Road	[34.70908,-82.25409]	(864)963-7732	(864)962-6062	https://www.homedepot.com/l/Simpsonville/SC/Simpsonville/29680/1124	Monday - 6:00 AM to 9:00 PM Tuesday - 6:00 AM to 9:00 PM Wednesday - 6:00 AM to 6:00 PM Thursday - 9:00 AM to 8:00 PM Friday - 6:00 AM to 9:00 PM Saturday - 6:00 AM to 9:00 PM Sunday - 8:00 AM to 8:00 PM
1126	Greer	United States	Greer	South Carolina	29687	1385 W Wade Hampton Blvd	[34.93793,-82.26697]	(864)848-6083	(864)968-1462	https://www.homedepot.com/l/Greer/SC/Greer/29650/1126	Monday - 6:00 AM to 9:00 PM Tuesday - 6:00 AM to 9:00 PM Wednesday - 6:00 AM to 6:00 PM Thursday - 9:00 AM to 8:00 PM Friday - 6:00 AM to 9:00 PM Saturday - 6:00 AM to 9:00 PM Sunday - 8:00 AM to 8:00 PM
1127	SW Greenville	United States	Gantt	South Carolina	29605	1339 S Pleasantburg Dr	[34.80062,-82.37487]	(864)236-0197	(864)236-1404	https://www.homedepot.com/l/SW-Greenville/SC/Greenville/29605/1127	Monday - 6:00 AM to 9:00 PM Tuesday - 6:00 AM to 9:00 PM Wednesday - 6:00 AM to 6:00 PM Thursday - 9:00 AM to 8:00 PM Friday - 6:00 AM to 9:00 PM Saturday - 6:00 AM to 9:00 PM Sunday - 8:00 AM to 8:00 PM
1129	Spartanburg	United States	Spartanburg	South Carolina	29301	121 Dorman Center Drive	[34.93597,-81.98552]	(864)574-2922	(864)595-5502	https://www.homedepot.com/l/Spartanburg/SC/Spartanburg/29301/1129	Monday - 6:00 AM to 9:00 PM Tuesday - 6:00 AM to 9:00 PM Wednesday - 6:00 AM to 6:00 PM Thursday - 9:00 AM to 8:00 PM Friday - 6:00 AM to 9:00 PM Saturday - 6:00 AM to 9:00 PM Sunday - 8:00 AM to 8:00 PM
1130	Seneca	United States	Seneca	South Carolina	29672	1614 Sandifer Blvd	[34.69179,-82.99534]	(864)886-0633	(864)985-7964	https://www.homedepot.com/l/Seneca/SC/Seneca/29678/1130	Monday - 6:00 AM to 9:00 PM Tuesday - 6:00 AM to 9:00 PM Wednesday - 6:00 AM to 6:00 PM Thursday - 9:00 AM to 8:00 PM Friday - 6:00 AM to 9:00 PM Saturday - 6:00 AM to 9:00 PM Sunday - 8:00 AM to 8:00 PM
1171	Mt. Pleasant	United States	Mount Pleasant	South Carolina	29466	2213 North Highway 17	[32.84133,-79.81540]	(843)972-6800	—	https://www.homedepot.com/l/Mt-Pleasant/SC/Mount-Pleasant/29466/1171	Monday - 6:00 AM to 9:00 PM Tuesday - 6:00 AM to 9:00 PM Wednesday - 6:00 AM to 6:00 PM Thursday - 9:00 AM to 8:00 PM Friday - 6:00 AM to 9:00 PM Saturday - 6:00 AM to 9:00 PM Sunday - 8:00 AM to 8:00 PM
6918	Easley	United States	Easley	South Carolina	29642	6607 Calhoun Memorial Hwy	[34.81941,-82.58671]	(864)306-0137	(864)850-2470	https://www.homedepot.com/l/Easley/SC/Easley/29640/6918	Monday - 6:00 AM to 9:00 PM Tuesday - 6:00 AM to 9:00 PM Wednesday - 6:00 AM to 6:00 PM Thursday - 9:00 AM to 8:00 PM Friday - 6:00 AM to 9:00 PM Saturday - 6:00 AM to 9:00 PM Sunday - 8:00 AM to 8:00 PM
8580	Florence	United States	Florence	South Carolina	29501	3051 West Radio Drive	[34.18760,-79.83965]	(843)661-2597	(843)661-8462	https://www.homedepot.com/l/Florence/SC/Florence/29501/8580	Monday - 6:00 AM to 9:00 PM Tuesday - 6:00 AM to 9:00 PM Wednesday - 6:00 AM to 6:00 PM Thursday - 9:00 AM to 8:00 PM Friday - 6:00 AM to 9:00 PM Saturday - 6:00 AM to 9:00 PM Sunday - 8:00 AM to 8:00 PM
8913	Lancaster	United States	Lancaster	South Carolina	29720	1116 Highway 9 Byp W	[34.73556,-80.79284]	(803)286-9700	(803)313-5368	https://www.homedepot.com/l/Lancaster/SC/Lancaster/29720/8913	Monday - 6:00 AM to 9:00 PM Tuesday - 6:00 AM to 9:00 PM Wednesday - 6:00 AM to 6:00 PM Thursday - 9:00 AM to 8:00 PM Friday - 6:00 AM to 9:00 PM Saturday - 6:00 AM to 9:00 PM Sunday - 8:00 AM to 8:00 PM

Explore other cities in South Carolina, United States

Aiken Anderson Bluffton Charleston Columbia Dentsville Easley Florence Gantt Garden City Greenville Greer Lancaster Lexington Mount Pleasant Myrtle Beach North Charleston North Myrtle Beach Rock Hill Sans Souci Seneca Simpsonville Spartanburg Summerville